Liquid Biopsy and Circulating Tumor DNA (ctDNA)

This dataset provides comprehensive records of liquid biopsy samples and circulating tumor DNA (ctDNA) analysis for cancer patients, including molecular findings, treatment details, and clinical outcomes. It enables longitudinal monitoring of minimal residual disease, treatment response, and resistance mutations, supporting research and clinical decision-making in precision oncology.

  • last updated 2 Nov 2025
  • by GoMask
The brief that made it

Longitudinal monitoring of cancer patients for minimal residual disease and treatment response

Sample rows

preview · 8 of 100 rows · all 17 columns
sample_idstringtreatment_responsestringctdna_levelfloatresistance_mutation_detectedbooleanresistance_mutation_liststringpatient_idstringcollection_datedatecancer_typestringstagestringminimal_residual_disease_detectedbooleantreatment_typestringtreatment_start_datedatesequencing_methodstringlaboratory_namestringreport_datedateclinician_idstringnotesstring
LB202401-001partial response3.52falseblankPAT10012024-01-05lungIIItruechemotherapy2023-12-15NGSGenomicDx Labs2024-01-06CLN5001Patient experienced mild nausea, MRD positive.
LB202401-002stable disease0falseblankPAT10022024-01-07breastIIfalseimmunotherapy2023-11-20digital PCRPrecision Oncology2024-01-08CLN5002No MRD detected; patient remains stable.
LB202401-003progressive disease7.41trueKRAS G12D, NRAS Q61KPAT10032024-01-09colorectalIVtruetargeted therapy2023-10-02NGSOncoSeq Diagnostics2024-01-10CLN5003Resistance mutations detected; recommend regimen change.
LB202401-004not evaluated0falseblankPAT10042024-01-10prostateIfalsechemotherapy2023-09-16digital PCRGenomicDx Labs2024-01-11CLN5004First biopsy for baseline testing.
LB202401-005partial response2.14falseblankPAT10052024-01-12lungIItrueimmunotherapy2023-12-10NGSOncoSeq Diagnostics2024-01-13CLN5005Low MRD detected, continue monitoring.
LB202401-006stable disease0falseblankPAT10022024-01-14breastIIfalseimmunotherapy2023-11-20digital PCRPrecision Oncology2024-01-15CLN5002No ctDNA detected, patient stable.
LB202401-007progressive disease6.75trueBRCA1 185delAGPAT10062024-01-16ovarianIIItruechemotherapy2023-12-03NGSGenomicDx Labs2024-01-17CLN5006Progression noted, resistance mutation present.
LB202401-008stable disease8.88trueEGFR T790MPAT10072024-01-18lungIVtruetargeted therapy2023-10-25NGSOncoSeq Diagnostics2024-01-19CLN5007EGFR T790M detected; patient under review.

What the 100 rows show

from the 100-row sample

Progressive disease (treatment response) stands out: 27 of its 27 rows have resistance_mutation_detected = true, against 2 of 73 for the rest.

  • 29%resistance_mutation_detected = true
  • 4.0median ctdna_level
  • 2sequencing methods
  • 3treatment types
  • 4stages
  • 5cancer types
Resistance mutation detected rate by treatment_responseresistance_mutation_detected = true
0%50%100%0%comple…0 of 130%partia…0 of 259%stable…2 of 22100%progre…27 of 270%not ev…0 of 13
ctdna_level100 rows, in bands of 5
03060521715412143102550ctdna_level →

Median 4.0, from 0.0 to 45.1.

resistance_mutation_list29 rows with a value · 71 left blank
  1. EGFR T790M6
  2. EGFR C797S3
  3. EGFR L858R3
  4. KRAS G12D3
  5. KRAS G12C2
  6. AR-V72
  7. KRAS G12C,EGFR T790M2
  8. EGFR T790M,KRAS G12C2
  9. KRAS G12D, NRAS Q61K1
  10. BRCA1 185delAG1
17 columns by typefrom the column list below
  • string 11
  • float 1
  • date 3
  • boolean 2

Columns

17 columns in four groups
blueprint · 17 columns
columntypedescriptionexample
Text 11 columns
sample_idstringUnique identifier for each liquid biopsy sampleuniqueLB202401-001
patient_idstringUnique identifier for the patient from whom the sample was collectedPAT1001
cancer_typestringType of cancer diagnosed in the patient (e.g., lung, breast, colorectal)5 typeslung
stagestringCancer stage at time of sample collection (e.g., I, II, III, IV)0 · I · II · III · IV · optionalIII
treatment_typestringType of treatment patient is receiving at time of sample (e.g., chemotherapy, immunotherapy, targeted therapy)3 types · optionalchemotherapy
treatment_responsestringClinical assessment of patient's response to treatment (e.g., partial response, stable disease, progressive disease)5 values · optionalpartial response
resistance_mutation_liststringComma-separated list of resistance mutations detected (e.g., EGFR T790M, KRAS G12C)optionalKRAS G12D, NRAS Q61K
sequencing_methodstringMethod used for ctDNA analysis (e.g., NGS, digital PCR)2 methods · optionalNGS
laboratory_namestringName of the laboratory performing the ctDNA test8 names · optionalGenomicDx Labs
clinician_idstringIdentifier for the clinician responsible for patient careoptionalCLN5001
notesstringAdditional comments or observations related to the sample or patientoptionalLow MRD detected.
Numbers 1 column
ctdna_levelfloatQuantitative level of circulating tumor DNA detected (ng/mL)0 or more · optional3.52
Dates and times 3 columns
collection_datedateDate the liquid biopsy sample was collected2024-01-05
treatment_start_datedateDate the current treatment regimen startedoptional2023-12-15
report_datedateDate the ctDNA test report was issuedoptional2024-01-06
True or false 2 columns
minimal_residual_disease_detectedbooleanIndicates if minimal residual disease (MRD) was detected in the sampleoptionaltrue
resistance_mutation_detectedbooleanIndicates if resistance mutations were detected in ctDNAoptionalfalse

Use it for

  • resistance mut…29%29 of 100 rowsmean ctdna level by t…0.0comp…6.5part…4.9stab…21.0prog…

    A healthcare dashboard

    The resistance_mutation_detected rate, ctdna_level by treatment_response and a breakdown of resistance_mutation_list. Excel, Power BI or Tableau.

  • Why do 29 of 100 rows have resistance_mutation_detected = true?

    A root-cause class exercise

    Hand out the rows and one question. The answer is in the data, not in the brief.

  • A software demo

    Believable samples with patient_id, collection_date and cancer_type to fill a screen in front of a buyer.

Not quite right?

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This dataset100 rows17 columns
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blueprint · liquid-biopsy-and-circulating-tumor-dna-ctdna

Behind this dataset

Same schema. As many rows as you need.

These 100 rows came out of a blueprint — 17 columns with generation rules behind each one. Open it in Data Factory to retune a column, add your own, wire in foreign keys, and run it at the size you actually need.

Rules it was built with
  • Sample ID unique per blood draw
  • Sample type: plasma, serum
  • Timepoint: baseline, on-treatment, post-treatment, surveillance
  • ctDNA detected: yes or no
  • Variant allele fraction (VAF) in plasma
  • Somatic mutations detected matching tumor
  • Emerging resistance mutations (e.g., T790M in EGFR)
  • Minimal residual disease (MRD) monitoring post-surgery
Rows
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Exports
CSV, JSON, JSONL, Parquet, SQL, Excel, TSV, XML
Licence
yours to use, including commercially
API slug
liquid-biopsy-and-circulating-tumor-dna-ctdna

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